Rabbit and rat C-reactive proteins bind apolipoprotein B-containing lipoproteins.

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Rabbit and rat C-reactive proteins bind apolipoprotein B-containing lipoproteins

Immobilized rabbit and rat C-reactive protein (CRP) were found to selectively bind apolipoprotein B (apoB)-containing lipoproteins (low density lipoprotein, LDL and very low density lipoprotein, VLDL) from whole serum in a manner similar to that previously reported with human CRP. In acute phase human serum the CRP is in a free form, not complexed with lipoprotein or any other macromolecular li...

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Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease

Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of atherosclerotic cardiovascular disease. Multiple unequivocal and orthogonal lines of evidence all converge on low-density lipoprotein and related particles as being the principal actors in the genesis of atherosclerosis. Here, we review the fundamental role of atherog...

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Comparison of four procedures for separating apolipoprotein A- and apolipoprotein B-containing lipoproteins in plasma.

Because lipoproteins containing apolipoprotein A (ApoA-I + ApoA-II) or apolipoprotein B (ApoB) seem to exert opposite effects as risk factors for coronary heart disease, we decided to determine the separability of these two major plasma lipoproteins by procedures originally designed to separate high-density from low- and very-low-density lipoproteins. The presumably ApoB-free lipoproteins isola...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1984

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.159.2.604